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Protein Coding Gene : Neurog2 neurogenin 2

Primary Identifier  MGI:109619 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  11924
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables E-box binding activity. Acts upstream of or within several processes, including generation of neurons; positive regulation of neuron differentiation; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo ectoderm; eye; and integumental system. Orthologous to human NEUROG2 (neurogenin 2).
PHENOTYPE: Homozygous null mice die after birth and have neuronal differentiation defects, affecting retinal development, spinal cord interneuron development and behavior. [provided by MGI curators]
  • synonyms:
  • neurogenin 2,
  • ngn2,
  • bHLHa8,
  • atonal homolog 4 (Drosophila),
  • Math4A,
  • Atoh4,
  • Neurog2,
  • MGD-MRK-39618

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

3 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

5 Driver For