Primary Identifier | MGI:1342290 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 20112 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Enables ribosomal protein S6 kinase activity. Acts upstream of or within several processes, including cardiac muscle cell apoptotic process; oocyte maturation; and regulation of gene expression. Located in cytoplasm and meiotic spindle. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; nervous system; and sensory organ. Orthologous to human RPS6KA2 (ribosomal protein S6 kinase A2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased response of heart to stress following transverse aortic constriction. [provided by MGI curators] |