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Allele : Raf1<tm2.1Ara> v-raf-leukemia viral oncogene 1; targeted mutation 2.1, Toshiyuki Araki
Primary Identifier  MGI:5445964 Allele Type  Targeted
Attribute String  Not Specified Gene  Raf1
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6NCrl)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector containing a loxP site, cDNA spanning exons 13 through 16, neo cassette, second loxP site and modified exon 13 was inserted into intron 12. The modified exon 13 contains nucleotide substitution(s) that result in the amino acid substitution of asparagine for aspartic acid at position 486 (D486N). Cre-mediated recombination removed the cDNA and neo cassette.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Raf1<D486N>,
  • Raf1<D486N>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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