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Publication : Nucleotide sequences of the human and mouse atrial natriuretic factor genes.

First Author  Seidman CE Year  1984
Journal  Science Volume  226
Issue  4679 Pages  1206-9
PubMed ID  6542248 Mgi Jnum  J:7667
Mgi Id  MGI:56136 Doi  10.1126/science.6542248
Citation  Seidman CE, et al. (1984) Nucleotide sequences of the human and mouse atrial natriuretic factor genes. Science 226(4679):1206-9
abstractText  Mouse and human atrial natriuretic factor (ANF) genes have been cloned and their nucleotide sequences determined. Each ANF gene consists of three coding blocks separated by two intervening sequences. The 5' flanking sequences and those encoding proANF are highly conserved between the two species, while the intervening sequences and 3' untranslated regions are not. The conserved sequences 5' of the gene may play an important role in the regulation of ANF gene expression.
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