Primary Identifier | MGI:2664670 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 244646 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables transmembrane transporter binding activity. Contributes to monoatomic cation channel activity and sour taste receptor activity. Involved in cellular response to acidic pH; detection of chemical stimulus involved in sensory perception of sour taste; and monoatomic cation transport. Part of cation channel complex and receptor complex. Colocalizes with cell surface. Is expressed in circumvallate papillae; cochlea; foliate papillae; and testis. Orthologous to human PKD1L3 (polycystin 1 like 3, transient receptor potential channel interacting). PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and grossly normal and exhibit normal taste responsiveness in various behavioral and electrophysiological tests of taste function. [provided by MGI curators] |