| First Author | Cebrat M | Year | 2004 |
| Journal | Cancer Lett | Volume | 206 |
| Issue | 1 | Pages | 107-13 |
| PubMed ID | 15019166 | Mgi Jnum | J:88778 |
| Mgi Id | MGI:3037137 | Doi | 10.1016/j.canlet.2003.10.024 |
| Citation | Cebrat M, et al. (2004) Wnt inhibitory factor-1: a candidate for a new player in tumorigenesis of intestinal epithelial cells. Cancer Lett 206(1):107-13 |
| abstractText | Using cDNA-Representational Difference Analysis it was found that expression of Opg, Ctse, Krt2-4, Fut-2, 24p3 and Wif-1 genes was elevated in intestinal adenomas as compared to normal epithelial cells of Apc(Min/+) mutant mice. Expression of Wif-1, which encodes Wnt inhibitory factor-1 was also detected in a number of tumor cell lines of epithelial cell origin including two human colon adenocarcinoma cell lines. The possible role of Wif-1 over-expression in the etiology of colorectal cancer is discussed. |
