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Protein Coding Gene : Sash1 SAM and SH3 domain containing 1
Primary Identifier  MGI:1917347 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  70097
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable G-protein alpha-subunit binding activity; mitogen-activated protein kinase kinase kinase binding activity; and molecular adaptor activity. Predicted to be involved in positive regulation of non-canonical NF-kappaB signal transduction and regulation of epithelial cell migration. Predicted to act upstream of or within several processes, including positive regulation of angiogenesis; positive regulation of signal transduction; and regulation of protein ubiquitination. Located in membrane. Human ortholog(s) of this gene implicated in dyschromatosis universalis hereditaria. Orthologous to human SASH1 (SAM and SH3 domain containing 1).
  • synonyms:
  • SAM and SH3 domain containing 1,
  • 1100001C18Rik,
  • RIKEN cDNA A330076K04 gene,
  • A330076K04Rik,
  • MGI:1915682,
  • RIKEN cDNA 2500002E12 gene,
  • RIKEN cDNA 1100001C18 gene,
  • MGI:2444711,
  • 2500002E12Rik,
  • Sash1
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