| Primary Identifier | MGI:2386400 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Gal3st1 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | 1,126 bp of the gene, including part of exon 2 and part of exon 3, was replaced with a PGK-neo cassette via homologous recombination. The targeted mutation disrupts the transmembrane domain and the 5'-3' phosphoadenosine 5'-phosphosulfate-binding motif. Northern blot analysis of brain RNA and RT-PCR analysis of testicular RNA showed that gene expression is abolished in homozygous mutant animals. |
