Primary Identifier | MGI:2181390 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Hnf1b |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A floxed neomycin selection cassette and an additional loxP site were inserted at the endogenous locus via homologous recombination. Deletion of the promoter region, the transcription initiation site, and exon 1 was achieved by the transient expression of cre recombinase in ES cells. |