Primary Identifier | MGI:5696731 | Allele Type | Targeted |
Attribute String | Conditional ready, Inserted expressed sequence, Reporter | Gene | Gt(ROSA)26Sor |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting construct inserted into the locus a CAG promoter; floxed STOP cassette; an HA tagged mutant G protein-coupled receptor (GPCR) sequence of the Galphas-coupled rat muscarinic 3 DREADD (designer receptor exclusively activated by designer drug), also referred to as R-s; a GFP reporter gene; and a cAMP responsive element activated by cAMP that drives expression of a luciferase reporter gene. |