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Allele : Hey2<tm1Mtc> hairy/enhancer-of-split related with YRPW motif 2; targeted mutation 1, Michael T Chin

Primary Identifier  MGI:2447620 Allele Type  Targeted
Attribute String  Null/knockout Gene  Hey2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence encompassing 551 nt of the proximal promoter and exon 1 through the majority of exon 3 was replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region encoded 75 residues composing the amino terminal, basic region, and most of the helix-loop-helix domain. Transcript was undetected by RT-PCR analysis of cardiac ventricles obtained from homozygous mutant embryos.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • CHF1<->,
  • CHF1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

11 Publication categories

Trail: Allele