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Allele : Wasf1<tm2Jsco> WASP family, member 1; targeted mutation 2, John D Scott

Primary Identifier  MGI:3714530 Allele Type  Targeted
Attribute String  Hypomorph Gene  Wasf1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
description  ES cell line = JSI-1.
molecularNote  A targeting vector was designed to place a neomycin cassette in intron 6, and delete amino acids 322-332 and 425-431 of exon 7. Protein levels are similar to wild-type as shown by immunoprecipitation, but the level of protein binding to Rac GTPase-activating protein (WRP) is reduced by 50%.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • wave <m>,
  • wave <m>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele