Primary Identifier | MGI:3714530 | Allele Type | Targeted |
Attribute String | Hypomorph | Gene | Wasf1 |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
description | ES cell line = JSI-1. |
molecularNote | A targeting vector was designed to place a neomycin cassette in intron 6, and delete amino acids 322-332 and 425-431 of exon 7. Protein levels are similar to wild-type as shown by immunoprecipitation, but the level of protein binding to Rac GTPase-activating protein (WRP) is reduced by 50%. |