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Protein Domain : Eukaryotic translation initiation factor 3 subunit H

Primary Identifier  IPR027524 Type  Family
Short Name  eIF3h
description  Eukaryotic translation initiation factor 3 subunit H (eIF3h) is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome [, ]. It is a non-peptidase homologue in peptidase family M67 (MEROPS identifier M67.971).Results suggest that eIF3h regulates cell growth and viability, and that over-expression of the gene may provide growth advantage to prostate, breast, and liver cancer cells [, , ].

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18 Protein Domain Regions