| First Author | Elango R | Year | 1996 |
| Journal | Mamm Genome | Volume | 7 |
| Issue | 5 | Pages | 340-3 |
| PubMed ID | 8661719 | Mgi Jnum | J:33162 |
| Mgi Id | MGI:80642 | Doi | 10.1007/s003359900099 |
| Citation | Elango R, et al. (1996) Generation and mapping of Mus spretus strain-specific markers for rapid genomic scanning. Mamm Genome 7(5):340-3 |
| abstractText | We describe here a set of genetic markers, based on IRS-PCR amplification difference, that are specifically designed for efficient, high throughput genetic mapping in [(M. domesticus x wild-derived) F1 x M. domesticus] interspecific backcrosses. 146 new genetic loci have been mapped, and strain distribution for these markers has been determined in 96 mouse strains. 103 (81%) of 127 tested markers are present only in one or more wild-derived strains, but absent in 76 other commonly used strains, demonstrating their utility in a variety of mouse pair combinations. Because of the ease of genotyping with this marker set, rapid genome scans for complex genetic trait loci involving crosses between wild-derived strains and other commonly used strains can now be carried out efficiently with large numbers of animals. |
