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Protein Coding Gene : Aanat arylalkylamine N-acetyltransferase
Primary Identifier  MGI:1328365 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  11298
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables arylamine N-acetyltransferase activity. Predicted to be involved in several processes, including cellular response to cAMP; melatonin biosynthetic process; and response to prostaglandin E. Predicted to act upstream of or within rhythmic process. Predicted to be located in cytosol and perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome. Orthologous to human AANAT (aralkylamine N-acetyltransferase).
PHENOTYPE: Mutations in this gene result in abnormal melatonin production. [provided by MGI curators]
  • synonyms:
  • N-acetyl transferase 4, pineal gland,
  • Aanat,
  • Nat4,
  • MGD-MRK-12779,
  • MGI:97280,
  • SNAT,
  • arylalkylamine N-acetyltransferase,
  • N-acetyl transferase 2, pineal gland,
  • MGD-MRK-12781,
  • N-acetyl transferase 4,
  • Nat-2
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