Primary Identifier | MGI:3698433 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 544717 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Involved in mitochondrial respiratory chain complex III assembly. Located in mitochondrion. Orthologous to human UQCC6 (ubiquinol-cytochrome c reductase complex assembly factor 6). PHENOTYPE: Mice homozygous for a null allele exhibit depletion of complex II in the mitochondria with a mild increase in circulating lactate level and reduced exercise tolerance. [provided by MGI curators] |