| Primary Identifier | MGI:107634 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 28036 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables U6 snRNA binding activity. Involved in ncRNA metabolic process; regulation of mRNA splicing, via spliceosome; and spermatogenesis. Acts upstream of or within germ cell proliferation; negative regulation of transcription by RNA polymerase II; and positive regulation of G1/S transition of mitotic cell cycle. Located in nucleus. Is expressed in several structures, including central nervous system; gonad; liver; sensory organ; and spleen. Orthologous to human LARP7 (La ribonucleoprotein 7, transcriptional regulator). PHENOTYPE: Mice homozygous for a null mutation display complete perinatal lethality and a decrease in primordial germ cell number and proliferation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
