First Author | Eisenman LM | Year | 2002 |
Journal | Brain Res | Volume | 952 |
Issue | 1 | Pages | 135-41 |
PubMed ID | 12363413 | Mgi Jnum | J:79488 |
Mgi Id | MGI:2388400 | Doi | 10.1016/s0006-8993(02)03184-0 |
Citation | Eisenman LM, et al. (2002) Acute ethanol administration produces specific patterns of localization of Fos-immunoreactivity in the cerebellum and inferior olive of two inbred strains of mice. Brain Res 952(1):135-41 |
abstractText | Genes play an important role in behavioral responses to ethanol. We examined the response of neurons within the inferior olivary complex (IO) and cerebellum of C57Bl6/J and C3H/HeJ mice to acute ethanol, using immunodetection of Fos (Fos-IR) protein as a marker of neuronal activation. The results demonstrate specific but different patterns of Fos-IR within the IO and cerebellum, especially lobule IX, in each strain. The Fos-IR banding pattern seen in the granule cells of lobule IX is aligned with a previously described banding pattern of Purkinje cells that constitutively expressed heat-shock protein-25 (HSP-25). |