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Allele : Dock8<m1> dedicator of cytokinesis 8; mutation 1

Primary Identifier  MGI:5749378 Allele Type  Spontaneous
Attribute String  Null/knockout Gene  Dock8
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  A C-to-T point mutation located in exon 47 results in a premature stop codon at the arginine codon (p.R2034*). This results in reduced levels of mRNA and absence of detectable levels of protein in bone marrow derived dendritic cells from homozygous mice. This mutation was found in mice carrying Nlrp10tm1Seis
  • mutations:
  • Single point mutation
  • synonyms:
  • Dock8<mu>,
  • Dock8<mu>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele