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Protein Coding Gene : Rab25 RAB25, member RAS oncogene family

Primary Identifier  MGI:1858203 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  53868
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable GTP binding activity; GTPase activity; and myosin V binding activity. Involved in epithelial cell morphogenesis. Predicted to be located in cytoplasmic vesicle; plasma membrane; and pseudopodium. Predicted to be active in Golgi apparatus and recycling endosome. Is expressed in gut; nasal cavity epithelium; skin; submandibular gland primordium; and urinary system. Orthologous to human RAB25 (RAB25, member RAS oncogene family).
PHENOTYPE: On a 129 background, virgin female homozygotes older than 10 months of age develop vaginal cancer while both male and female homozygotes develop distal esophageal stricture due to squamous cell hyperplasia. [provided by MGI curators]
  • synonyms:
  • Rab25,
  • AV012978,
  • MGI:2139927,
  • expressed sequence AV012978,
  • RAB25, member RAS oncogene family

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For