Primary Identifier | IPR032377 | Type | Domain |
Short Name | STAR_dimer |
description | This entry represents the homodimerisation domain of the STAR (signal transducer and activator of RNA) proteins. Quaking is a prototypical member of the STAR family, which plays key roles in post-transcriptional gene regulation by controlling mRNA translation, stability and splicing []. Quaking-dimer is a helix-turn-helix dimer with an additional helix in the turn region. The dimerisation of quaking is required for adequate RNA-binding []. |