| First Author | Kaluz S | Year | 1996 |
| Journal | Gene | Volume | 172 |
| Issue | 2 | Pages | 313-4 |
| PubMed ID | 8682324 | Mgi Jnum | J:33726 |
| Mgi Id | MGI:81203 | Doi | 10.1016/0378-1119(96)00195-3 |
| Citation | Kaluz S, et al. (1996) Heterogeneity in the third intracytoplasmic region of the oxytocin receptor-encoding gene. Gene 172(2):313-4 |
| abstractText | The oxytocin receptor (OTR), a member of the seven-transmembrane domain guanine-nucleotide-binding protein (G protein) coupled receptor family plays a central role in lactation, ovarian cyclicity and reproductive behaviour. Recent cloning and sequencing unexpectedly revealed that the third intracytoplasmic region (3ICR) of the sheep receptor has 3 and 2 additional amino acids (aa) relative to the rat and human receptors, respectively. We have now confirmed, by sequencing polymerase chain reaction (PCR)-derived genomic fragments coding for the OTR 3ICR from a variety of ruminant and non-ruminant species, that additional aa are a general phenomenon in ruminants. |
