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Protein Domain : Dipeptidase 1

Primary Identifier  IPR028536 Type  Family
Short Name  Dpep1
description  Dipeptidase 1 (Dpep1), renal dipeptidase (RDP), or microsomal dipeptidase is a zinc-dependent metalloenzyme that hydrolyses a wide range of dipeptides. It is implicated in the renal metabolism of glutathione and its conjugates. It converts leukotriene D4 to leukotriene E4 and it may play an important role in the regulation of leukotriene activity []. Renal dipeptidase seems to be evolutionary related to hypothetical proteins in the PQQ biosynthesis operons of Acinetobacter calcoaceticus and Klebsiella pneumoniae [].

0 Child Features

1 Parent Features

4 Protein Domain Regions