| Primary Identifier | MGI:1858195 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 51810 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables RNA polymerase II C-terminal domain binding activity; nucleic acid binding activity; and promoter-specific chromatin binding activity. Involved in several processes, including RNA localization to chromatin; cellular response to leukemia inhibitory factor; and regulation of gene expression. Acts upstream of or within with a positive effect on mRNA metabolic process. Acts upstream of or within cardiac muscle cell development. Located in dendrite cytoplasm; inactive sex chromosome; and nucleus. Part of ribonucleoprotein complex. Is expressed in several structures, including branchial arch; future brain; limb primordium; tail bud; and unsegmented mesenchyme. Used to study developmental and epileptic encephalopathy 54. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 54. Orthologous to human HNRNPU (heterogeneous nuclear ribonucleoprotein U). PHENOTYPE: Mice homozygous for a gene trap allele display embryonic lethality, delayed embryonic development, and failure of chorioallantoic fusion. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
