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Protein Coding Gene : Cxcr5 C-X-C motif chemokine receptor 5

Primary Identifier  MGI:103567 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  12145
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable C-C chemokine binding activity and C-C chemokine receptor activity. Acts upstream of or within leukocyte chemotaxis and lymph node development. Located in external side of plasma membrane. Is expressed in several structures, including central nervous system; extraembryonic component; liver; and retina. Orthologous to human CXCR5 (C-X-C motif chemokine receptor 5).
PHENOTYPE: Homozygous null mutants lack inguinal lymph nodes, have a few abnormal or no Peyer's patches, morphologically altered primary lymphoid follicles and no functional germinal centers in their spleen. [provided by MGI curators]
  • synonyms:
  • Cxcr5,
  • MGD-MRK-24452,
  • G-protein coupled receptor 6,
  • Burkitt lymphoma receptor 1,
  • C-X-C motif chemokine receptor 5,
  • MGD-MRK-16340,
  • MGI:99562,
  • Gpcr6,
  • CXCR-5,
  • Blr1

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For