| Primary Identifier | MGI:2146634 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 106407 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables bile acid transmembrane transporter activity; protein heterodimerization activity; and protein homodimerization activity. Involved in bile acid and bile salt transport. Acts upstream of or within organic substance transport. Located in basolateral plasma membrane and endoplasmic reticulum membrane. Part of protein-containing complex. Is expressed in midgut and small intestine. Human ortholog(s) of this gene implicated in progressive familial intrahepatic cholestasis. Orthologous to human SLC51A (solute carrier family 51 member A). PHENOTYPE: Mice homozygous for disruptions in this gene exhibit growth retardation. In addition, one mutant exhibits impaired intestinal bile acid transport. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
