First Author | Ferrara N | Year | 1999 |
Journal | Nat Med | Volume | 5 |
Issue | 12 | Pages | 1359-64 |
PubMed ID | 10581076 | Mgi Jnum | J:58723 |
Mgi Id | MGI:1349524 | Doi | 10.1038/70928 |
Citation | Ferrara N, et al. (1999) Clinical applications of angiogenic growth factors and their inhibitors. Nat Med 5(12):1359-64 |
abstractText | Promoting the formation of new collateral vessels in ischemic tissues using angiogenic growth factors (therapeutic angiogenesis) is a an exciting frontier of cardiovascular medicine. Conversely, inhibition of the action of key regulators of angiogenesis, such as VEGF, constitutes a promising approach for the treatment of solid tumors and intraocular neovascular syndromes. These concepts are being tested now in clinical trials. |