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Publication : Clinical applications of angiogenic growth factors and their inhibitors.

First Author  Ferrara N Year  1999
Journal  Nat Med Volume  5
Issue  12 Pages  1359-64
PubMed ID  10581076 Mgi Jnum  J:58723
Mgi Id  MGI:1349524 Doi  10.1038/70928
Citation  Ferrara N, et al. (1999) Clinical applications of angiogenic growth factors and their inhibitors. Nat Med 5(12):1359-64
abstractText  Promoting the formation of new collateral vessels in ischemic tissues using angiogenic growth factors (therapeutic angiogenesis) is a an exciting frontier of cardiovascular medicine. Conversely, inhibition of the action of key regulators of angiogenesis, such as VEGF, constitutes a promising approach for the treatment of solid tumors and intraocular neovascular syndromes. These concepts are being tested now in clinical trials.
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