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Protein Coding Gene : Trmt6 tRNA methyltransferase 6

Primary Identifier  MGI:1914176 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  66926
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to be involved in tRNA methylation. Predicted to act upstream of or within tRNA processing. Predicted to be part of tRNA (m1A) methyltransferase complex. Predicted to be active in nucleus. Is expressed in brain ventricular layer; cerebral cortex subventricular zone; olfactory epithelium; submandibular gland primordium; and thymus primordium. Orthologous to human TRMT6 (tRNA methyltransferase 6 non-catalytic subunit).
PHENOTYPE: Mice homozygous for a null allele exhibit decreased CD4+ T cells and stimulated T cell proliferation. [provided by MGI curators]
  • synonyms:
  • MGI:2139353,
  • Trmt6,
  • MGI:2139161,
  • 3300001M20Rik,
  • expressed sequence AW492787,
  • RIKEN cDNA 3300001M20 gene,
  • mKIAA1153,
  • expressed sequence AU016412,
  • AW492787,
  • tRNA methyltransferase 6,
  • AU016412

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For