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Protein Coding Gene : Adgre1 adhesion G protein-coupled receptor E1

Primary Identifier  MGI:106912 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  13733
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to act upstream of or within adaptive immune response and signal transduction. Located in external side of plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system; intestine; and liver. Orthologous to human ADGRE1 (adhesion G protein-coupled receptor E1).
PHENOTYPE: Homozygous null mice fail to develop peripheral tolerance after inoculation with antigen because of a lack of efferent regulatory T cell development. [provided by MGI curators]
  • synonyms:
  • Adgre1,
  • EGF-like module containing, mucin-like, hormone receptor-like sequence 1,
  • MGI:105054,
  • glycoprotein f4/80 protein,
  • lymphocyte antigen 71,
  • MGI:106663,
  • MGD-MRK-35122,
  • Ly71,
  • MGD-MRK-32093,
  • F4/80,
  • TM7LN3,
  • MGD-MRK-35373,
  • adhesion G protein-coupled receptor E1,
  • Emr1,
  • Gpf480,
  • DD7A5-7,
  • EGF-TM7

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

2 Driver For