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Protein Coding Gene : Afg3l1 AFG3-like AAA ATPase 1

Primary Identifier  MGI:1928277 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  114896
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable metalloendopeptidase activity. Involved in protein processing. Acts upstream of or within cristae formation; mitochondrial fusion; and mitochondrial protein processing. Located in mitochondrial inner membrane. Part of m-AAA complex. Orthologous to human AFG3L1P (AFG3 like matrix AAA peptidase subunit 1, pseudogene).
PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and overtly normal with no detectable myelination defects or axonal degeneration in the brain and spinal cord and normal mitochondria in the spinal cord. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 1700047G05 gene,
  • RIKEN cDNA 3110061K15 gene,
  • MGI:1914568,
  • MGI:1920450,
  • 1700047G05Rik,
  • AFG3-like AAA ATPase 1,
  • Afg3l1,
  • 3110061K15Rik

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Canonical gene --> Transcripts in specific strains.

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