Primary Identifier | MGI:3838017 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Pard3 |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Germ line, cre mediated recombination was used to remove the neo cassette and exon 3. Deletion of this exon results in a frame-shift mutation and premature termination in the CR1 domain. The absence of protein expression was confirmed by western blot analysis on E11.5 embryo extracts. |