|  Help  |  About  |  Contact Us

Protein Coding Gene : Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5

Primary Identifier  MGI:1935129 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  93762
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and histone octamer slider activity. Predicted to contribute to histone binding activity. Involved in negative regulation of transcription by RNA polymerase I; positive regulation of DNA replication; and rDNA heterochromatin formation. Acts upstream of or within cellular response to leukemia inhibitory factor; chromatin remodeling; and positive regulation of DNA-templated transcription. Located in nucleus. Part of NoRC complex; chromatin silencing complex; and pericentric heterochromatin. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human SMARCA5 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5).
PHENOTYPE: Homozygous mutant mice die during early embryonic development. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA D030040M08 gene,
  • RIKEN cDNA 4933427E24 gene,
  • MGI:3586540,
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5,
  • MGI:1918447,
  • 4933427E24Rik,
  • RIKEN cDNA D330027N15 gene,
  • modifier of murine metastable epialleles, D4,
  • D030040M08Rik,
  • MommeD4,
  • Snf2h,
  • Smarca5,
  • D330027N15Rik,
  • MGI:2443329,
  • MGI:2441934

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

12 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For