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Allele : Slc6a3<tm1.1Emfu> solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; targeted mutation 1.1, Ernst-Martin Fuchtbauer
Primary Identifier  MGI:7518352 Allele Type  Targeted
Gene  Slc6a3 Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  The C-terminal PDZ-binding sequence LKV was substituted with alanines (AAA) in exon 15. Silent restriction enzyme sites were also introduced along with a loxP-flanked neomycin resistance gene upstream of exon 15. The neomycin cassette was deleted via cre-mediated recombination. Quantitative real-time PCR showed normal mRNA levels in midbrain tissue.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • DAT-AAA,
  • DAT-AAA
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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