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Protein Coding Gene : Slc34a2 solute carrier family 34 (sodium phosphate), member 2
Primary Identifier  MGI:1342284 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  20531
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables sodium:phosphate symporter activity. Acts upstream of or within in utero embryonic development and phosphate ion transport. Located in apical plasma membrane and brush border. Is expressed in several structures, including egg cylinder; genitourinary system; small intestine; and tooth. Human ortholog(s) of this gene implicated in pulmonary alveolar microlithiasis. Orthologous to human SLC34A2 (solute carrier family 34 member 2).
PHENOTYPE: Homozygous null mice display embryonic lethality, embryonic growth arrest, failure of embryo turning and somitogenesis, impaired placental development and impaired yolk sac vascular remodeling. [provided by MGI curators]
  • synonyms:
  • DNA segment, Chr 5, ERATO Doi 227, expressed,
  • Npt2b,
  • D5Ertd227e,
  • MGI:1098602,
  • Slc34a2,
  • type IIb Na/Picotransporter,
  • solute carrier family 34 (sodium phosphate), member 2,
  • AA536683,
  • expressed sequence AA536683,
  • MGI:2140766,
  • NaPi-2b
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Features --> Cross References

Genome

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4 Involved In Mutations

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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7 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

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Phenotype

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