|  Help  |  About  |  Contact Us

Protein Coding Gene : Plxna3 plexin A3

Primary Identifier  MGI:107683 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  18846
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables semaphorin receptor activity. Involved in nervous system development; positive regulation of cytoskeleton organization; and semaphorin-plexin signaling pathway. Acts upstream of or within several processes, including hippocampus development; negative regulation of axon extension involved in axon guidance; and neuron development. Predicted to be located in plasma membrane. Predicted to be part of semaphorin receptor complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; peripheral nervous system; and sensory organ. Orthologous to human PLXNA3 (plexin A3).
PHENOTYPE: Mice homozygous for disruptions in this gene possess misdirected axons in the hippocampus. They are, otherwise, indistinguishable from wild-type mice. [provided by MGI curators]
  • synonyms:
  • MGI:109627,
  • Plxna3,
  • Plxa3,
  • PlexA3,
  • plexin A3,
  • Plxn4,
  • MGD-MRK-36258,
  • plexin 3,
  • Plxn3,
  • SEX,
  • MGD-MRK-39626

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For