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Publication : Targeting the epigenome for treatment of cancer.

First Author  Geutjes EJ Year  2012
Journal  Oncogene Volume  31
Issue  34 Pages  3827-44
PubMed ID  22139071 Mgi Jnum  J:187795
Mgi Id  MGI:5438197 Doi  10.1038/onc.2011.552
Citation  Geutjes EJ, et al. (2012) Targeting the epigenome for treatment of cancer. Oncogene 31(34):3827-44
abstractText  Cancer genome analyses have revealed that the enzymes involved in epigenetic gene regulation are frequently deregulated in cancer. Here we describe the enzymes that control the epigenetic state of the cell, how they are affected in cancer and how this knowledge can be exploited to treat cancer with a new arsenal of selective therapies.
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