First Author | Geutjes EJ | Year | 2012 |
Journal | Oncogene | Volume | 31 |
Issue | 34 | Pages | 3827-44 |
PubMed ID | 22139071 | Mgi Jnum | J:187795 |
Mgi Id | MGI:5438197 | Doi | 10.1038/onc.2011.552 |
Citation | Geutjes EJ, et al. (2012) Targeting the epigenome for treatment of cancer. Oncogene 31(34):3827-44 |
abstractText | Cancer genome analyses have revealed that the enzymes involved in epigenetic gene regulation are frequently deregulated in cancer. Here we describe the enzymes that control the epigenetic state of the cell, how they are affected in cancer and how this knowledge can be exploited to treat cancer with a new arsenal of selective therapies. |