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Publication : The expression pattern of tomoregulin-1 in urodele limb regeneration and mouse limb development.

First Author  Morais da Silva S Year  2001
Journal  Mech Dev Volume  104
Issue  1-2 Pages  125-8
PubMed ID  11404089 Mgi Jnum  J:70066
Mgi Id  MGI:2136137 Doi  10.1016/s0925-4773(01)00362-8
Citation  Morais da Silva S, et al. (2001) The expression pattern of tomoregulin-1 in urodele limb regeneration and mouse limb development. Mech Dev 104(1-2):125-8
abstractText  Tomoregulin-1 (TMEFF1) was first identified as a gene implicated in pituitary secretion in Xenopus laevis. The predicted structure of TMEFF1 is that of a transmembrane protein with a highly conserved cytoplasmic tail, two follistatin domains and one modified EGF domain in its extracellular region. We report the cloning of the newt orthologue, and show that the expression of TMEFF1 is upregulated in the blastema during limb regeneration, and is also expressed in mouse embryonic limb development.
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