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Allele : Mest<tm1Masu> mesoderm specific transcript; targeted mutation 1, M Azim Surani

Primary Identifier  MGI:2181803 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Mest
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence encompassing all of exons 3 through 8 and a portion of exon 9 was replaced with a cassette containing an IRES-lacZ-neo fusion gene. RT-PCR analysis of total embryonic RNA showed an absence of normal transcript in animals possessing a targeted paternal allele and a silenced wild-type maternal allele. Paternal transmission of this allele yielded a lacZ expression pattern similar to that of the endogenous gene.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Mest<tm1Lef>,
  • Mest<tm1Lef-pat>,
  • Mest<+/->,
  • Mest<+/->,
  • Mest<tm1Lef-pat>,
  • Mest<tm1Lef>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

11 Publication categories

Trail: Allele