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Protein Coding Gene : Tnr tenascin R

Primary Identifier  MGI:99516 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  21960
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable integrin binding activity. Involved in several processes, including modulation of chemical synaptic transmission; negative regulation of neuron projection development; and regulation of cell migration. Acts upstream of or within several processes, including locomotory exploration behavior; modulation of chemical synaptic transmission; and negative regulation of axon extension involved in regeneration. Located in cell surface; membrane raft; and perineuronal net. Part of tenascin complex. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in several structures, including aorta tunica media; brain; heart; urinary system; and ventral grey horn. Orthologous to human TNR (tenascin R).
PHENOTYPE: In spite of having decreased conduction velocity in the optic nerve and ultrastrucural alterations within the hippocampus, homozygous null mice are viable, fertile, and display normal behavior. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-16293,
  • Tnr,
  • TN-R,
  • restrictin,
  • J1-tenascin,
  • janusin,
  • tenascin R

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For