Primary Identifier | MGI:3046866 | Allele Type | Gene trapped |
Attribute String | Null/knockout, Reporter | Gene | Capn3 |
Transmission | Germline | Strain of Origin | 129S5/SvEvBrd |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Lexicon |
molecularNote | A gene trap vector containing a neo-btk disrupted the gene by integrating into intron 1, thereby introducing premature stop codons after transcription. No gene products were detected by RT-PCR, including any splice variants. Western blot confirmed absence of full-length protein and fusion proteins of any size. |