| Primary Identifier | MGI:1918685 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 71435 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable GTPase activator activity. Acts upstream of or within regulation of endocytosis. Located in plasma membrane. Is expressed in central nervous system; dorsal root ganglion; and neural retina. Orthologous to human ARHGAP21 (Rho GTPase activating protein 21). PHENOTYPE: Mice homozygous for a gene trap allele exhibit die by E8. Mice heterozygous for the allele exhibit enhanced egress of HSC from the bone marrow resulting in decreased red blood cells, hemoglobin and platelets but increased leukocytes and neutrophils. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
