| Primary Identifier | MGI:104753 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 269116 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Enables protein binding activity involved in heterotypic cell-cell adhesion. Involved in paranodal junction assembly. Acts upstream of or within several processes, including neuron development; protein localization to axon; and transmission of nerve impulse. Located in several cellular components, including main axon; paranodal junction; and septate junction. Is expressed in nervous system and neural retina. Orthologous to human NFASC (neurofascin). PHENOTYPE: Mice homozygous for a null allele die within 6 to 7 days of birth, exhibit reduced nerve conduction velocity and abnormal paranodal junction formation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
