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Allele : Tg(Rr279-GH1)11Mrub transgene insertion 11, Marcelo Rubinstein

Primary Identifier  MGI:7341856 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Rr279-GH1)11Mrub
Is Recombinase  false Is Wild Type  false
molecularNote  The transgene contains the following elements: a neuron-specific enhancers-containing region 9-13 kb upstream of the Pomc gene transcription start site with enhancer Rr280 deleted but Rr279 still present, the Herpes simplex virus TK gene minimal promoter and the human growth hormone gene gene. The transgene is expressed in hypothalamic arcuate neurons but not in pituitary melanotrophs and corticotrophs during embryonic development.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele