Primary Identifier | MGI:7341856 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Rr279-GH1)11Mrub |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The transgene contains the following elements: a neuron-specific enhancers-containing region 9-13 kb upstream of the Pomc gene transcription start site with enhancer Rr280 deleted but Rr279 still present, the Herpes simplex virus TK gene minimal promoter and the human growth hormone gene gene. The transgene is expressed in hypothalamic arcuate neurons but not in pituitary melanotrophs and corticotrophs during embryonic development. |