| Primary Identifier | MGI:1934135 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 84112 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables G protein-coupled receptor activity. Involved in G protein-coupled receptor signaling pathway. Acts upstream of or within several processes, including macrophage activation involved in immune response; regulation of angiotensin metabolic process; and renin secretion into blood stream. Predicted to be located in cell surface. Predicted to be active in plasma membrane. Is expressed in neural retina and retina. Orthologous to human SUCNR1 (succinate receptor 1). PHENOTYPE: Mice homozygous for a knockout allele exhibit decreased renin plasma and kidney levels upon high-glucose stimulation in a diabetic or non-diabetic model. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
