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Protein Domain : Nuclear receptor coactivator 2

Primary Identifier  IPR028822 Type  Family
Short Name  NCOA2
description  Nuclear receptor coactivator 2 (NCOA2, also known as Tif2) belongs to the SRC/p160 nuclear receptor coactivator family, which contains proteins that are ligand-dependent transcription factors []. These receptors can function as molecular switches [].NCOA2 is a transcriptional coactivator for steroid receptors and nuclear receptors. It functions as a coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1) []. Together with NCOA1, it is required to control energy balance between white and brown adipose tissues [].

0 Child Features

1 Parent Features

14 Protein Domain Regions