| Primary Identifier | MGI:88543 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 12995 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables beta-catenin binding activity; kinase activity; and protein phosphatase regulator activity. Predicted to be involved in regulation of cell cycle and regulation of protein localization to plasma membrane. Predicted to act upstream of or within Wnt signaling pathway; apoptotic process; and rhythmic process. Predicted to be located in nucleoplasm. Predicted to be part of PcG protein complex; Sin3-type complex; and protein kinase CK2 complex. Predicted to be active in PML body and cytosol. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to several human genes including CSNK2A1 (casein kinase 2 alpha 1). PHENOTYPE: Mice homozygous for the null in the major catalytic subunit die by E11.5 and exhibit defects in neural, cardiac and limb development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
