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Protein Coding Gene : Actn2 actinin alpha 2
Primary Identifier  MGI:109192 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  11472
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables several functions, including LIM domain binding activity; nuclear receptor coactivator activity; and transmembrane transporter binding activity. Involved in cardiac muscle cell development; positive regulation of endocytic recycling; and protein localization to plasma membrane. Located in Z disc. Is expressed in several structures, including corpus striatum; face; heart; musculature; and trunk somite. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular cardiomyopathy; congenital myopathy 8; and dilated cardiomyopathy 1AA. Orthologous to human ACTN2 (actinin alpha 2).
  • synonyms:
  • actinin alpha 2,
  • MGD-MRK-38236,
  • RIKEN cDNA 1110008F24 gene,
  • Actn2,
  • MGI:1920965,
  • 1110008F24Rik
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

15 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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