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Protein Coding Gene : Chst2 carbohydrate sulfotransferase 2

Primary Identifier  MGI:1891160 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  54371
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables sulfotransferase activity. Involved in positive regulation of leukocyte tethering or rolling. Predicted to be located in Golgi apparatus; cytosol; and nucleoplasm. Predicted to be active in trans-Golgi network. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and sensory organ. Orthologous to human CHST2 (carbohydrate sulfotransferase 2).
PHENOTYPE: Mice homozygous for a knock-out allele display decreased lymphocyte binding to peripheral lymph node high endothelial venules, and significantly reduced lymphocyte homing to Peyer's patches, peripheral and mesenteric lymph nodes. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA C130041E03 gene,
  • MGI:2444728,
  • MGI:2143044,
  • MGI:2143292,
  • N-acetylglucosamine-6-O-sulfotransferase,
  • Gn6st,
  • Chst2,
  • C130041E03Rik,
  • AW121776,
  • AI428561,
  • expressed sequence AI428561,
  • GST-2,
  • expressed sequence AW121776,
  • carbohydrate sulfotransferase 2

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For