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Publication : Kidney complications in EMC virus-induced diabetes in conventional DBA/2 male mice.

First Author  Shichinohe K Year  1990
Journal  Jikken Dobutsu Volume  39
Issue  1 Pages  113-6
PubMed ID  2154384 Mgi Jnum  J:25879
Mgi Id  MGI:73588 Doi  10.1538/expanim1978.39.1_113
Citation  Shichinohe K, et al. (1990) Kidney complications in EMC virus-induced diabetes in conventional DBA/2 male mice. Jikken Dobutsu 39(1):113-6
abstractText  Conventional DBA/2 male mice of about 9 weeks of age were inoculated by intraperitoneally injecting EMC virus M variant (10(4) TCID50/0.1 ml/animal) which is passaged in mice. The mice which tested positive for glycosuria and hyperglycemia were examined histopathologically 2 or 5 months after inoculation. The kidneys were examined for thickening of Bowman's capsule and the mesangial matrix. These changes were more clearly observable 5 months after inoculation than they were 2 months after inoculation.
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