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Protein Coding Gene : Abra actin-binding Rho activating protein

Primary Identifier  MGI:2444891 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  223513
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables actin binding activity. Involved in positive regulation of Rho protein signal transduction. Acts upstream of or within positive regulation of transcription by RNA polymerase II and protein import into nucleus. Located in actin cytoskeleton and myofibril. Is expressed in embryo; heart; hindlimb muscle; and skeletal muscle. Orthologous to human ABRA (actin binding Rho activating protein).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired arteriogenesis following occlusion. [provided by MGI curators]
  • synonyms:
  • C130068O12Rik,
  • actin-binding Rho activating protein,
  • STARS,
  • RIKEN cDNA C130068O12 gene,
  • Abra

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For